The LabOnTheCheap blog came about as a result of explaining to various groups that we made great microfluidic chambers using parafilm with a cheap $150 knife printer that normally is used for cutting out stickers in arts and crafts projects, and then we sealed the microfluidic device with either nail-polish or cheap UV glue cured […]
Electroporation is a powerful alternative to heat shock for delivering small molecules such as plasmids across cell membranes. By application of an electrical field netivetly charged DNA is forced into elector-competent cells by an electrohoresis-type effect. Electroporators can be expensive, generally over $2000, hence the popularity of more chemical solutions such as heat shock. Enter […]
Want to do portable florescence spectroscopy on the cheap? Hojeong Yu, Yafang Tan, and Brian T. Cunningham wrote a 2014 paper that demonstrates that a smartphone camera, attached to a set of optical components that provide wavelength dispersion and a green laser pointer, can function as a sensitive fluorescence spectrometer.
Dr. Joe Alvin wrote in to let us know about an interesting blog post on the finances of science by Dr. Michael Johnson, from the Department of Immunobiology at the University of Arizona. The article lays out how the proceeds from a NIH grant are spent running a lab. The grant discussed worth ~2 million dollars […]
This week the Harris Lab at Brown put up a paper on the creation of a 3D-printed droplet generator. The system is based off a previously published design by David Harris which generates droplets on the scale of 1 mm. This new system now provides ample open-source instructions, and is fabricated with a 3D printer bringing the […]