Open Spin Microscopy

Awhile back we talked about OpenSPIM, which has a great step by step tutorial on how to make a light-sheet microscope.

In the same vein there is Open Spin Microscopy, a website with several DIY light sheet microscopy projects including a much simpler optical tomography design.

The website can be a little tricky to use, and much of the information you want is actually accessed by clicking on the “Sub-Systems header”. However if you get things built, then much like OpenSPIM the software to operate these devices is open source and designed for Micro-Manager which is nice and easy.

Make Your Own Light Sheet Microscope

Thinking about light sheet microscopy? Openspim.org gives you fantastically detailed assembly instructions to create your very own Selective Plane Illumination Microscope.

Credit to Dr. Guillaume Duclos for pointing this resource out. Don’t forget to check out the paper on this project put out by Peter Pitrone, Johannes Schindelin, Luke Stuyvenberg, Stephan Preibisch, Michael Weber, Kevin Eliceiri, Jan Huisken, and Pavel Tomancak