Incu-Stream: Inverted Bright-Field Microscopy and Automated Mechanical Scanning for just $184

Incu-Stream is an open-hardware microscopy setup designed for bright-field cell imaging of incubated microplates. The design is all laid out in a paper written by Güray Gürkan and Koray Gürkan, with nothing hidden in a supplementary packet this time. The system is specifically aimed at creating a microplate compatible inverted bright-field microscope system that can […]

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Ytterbium laser for $13,000.

One of the largest obstacles to two-photon DIY microscopy is the acquisition of a pulsed laser system, which generally hits the $100,000 range. Evan Perillo, Justin McCracken, Daniel Fernée, John Goldak, Flor Medina, David Miller, Hsin-Chih Yeh, and Andrew Dunn have a 2016 paper detailing the construction and characterization of a Ytterbium laser at  1060 […]

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DIY Fluorescence Smartphone Microscopy

We’ve covered several portable microscopy setups before, including Foldscope, wooden scope, and our favorite these little UV magnifiers. We like the latter so much because it is capable of both white light, and UV light, and we found we were capable of doing a little bit of fluorescence microscopy on it. That’s where a 2017 […]

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A Workhorse for 18k: DIY Microscopy with Flexiscope

The Flexiscope is DIY microscope that can be easily converted from upright to inverted configurations in “under 30 minutes”. It’s capable of oblique infrared illumination imaging, multi-channel fluorescent imaging, automated 3D scanning, and even has an electrophysiology configuration. The paper, written by Amy Courtney, Luke Alvey , George Merces, and Mark Pickering which details the […]

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DIY Cerna Components from Thorlabs

Do you love the idea of DIY microscopy but nervous about biting off more than you can chew? Thorlabs’ Cerna support for DIY microscopy is a great resource for easing you into it–think of it as training wheels for optical set ups. The Thorlabs Cerna microscope is a modular modular microscopy platform, but it’s surrounded […]

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