A bicycle inner tube under a breadboard can be sufficient to isolate building vibrations

In many cases equipment is set up on vibration dampened tables. In microscopy, these optical tables, in the shape of a giant metal floating breadboard are ubiquitous, and expensive. These optical tables cost several thousand dollars from the cheapest suppliers. However, if microscopes are not mechanically isolated, oscillations attenuate the quality of images. There’s an […]

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Incu-Stream: Inverted Bright-Field Microscopy and Automated Mechanical Scanning for just $184

Incu-Stream is an open-hardware microscopy setup designed for bright-field cell imaging of incubated microplates. The design is all laid out in a paper written by Güray Gürkan and Koray Gürkan, with nothing hidden in a supplementary packet this time. The system is specifically aimed at creating a microplate compatible inverted bright-field microscope system that can […]

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Ytterbium laser for $13,000.

One of the largest obstacles to two-photon DIY microscopy is the acquisition of a pulsed laser system, which generally hits the $100,000 range. Evan Perillo, Justin McCracken, Daniel Fernée, John Goldak, Flor Medina, David Miller, Hsin-Chih Yeh, and Andrew Dunn have a 2016 paper detailing the construction and characterization of a Ytterbium laser at  1060 […]

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DIY Fluorescence Smartphone Microscopy

We’ve covered several portable microscopy setups before, including Foldscope, wooden scope, and our favorite these little UV magnifiers. We like the latter so much because it is capable of both white light, and UV light, and we found we were capable of doing a little bit of fluorescence microscopy on it. That’s where a 2017 […]

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