Upgrade a 2-photon microscope with high-speed FLIM for $2352

Fluorescence-lifetime imaging microscopy (FLIM) is a microscopy technique used to measure the lifetime of a fluorophore rather than its intensity. Sensitive to the sample region’s micro-environment, lifetime measurements aren’t limited to measuring molecule concentration like traditional microscopy, but can also indicate environmental effects such as pH or viscosity. Additionally, this technique is not as affected […]

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A low cost microfabrication toolbox

If you are interested in working with microfluidics and are having difficulty getting started, check out a paper by Jérôme Charmet, Rui Rodrigues, Ender Yildirim, Pavan Challa, Benjamin Roberts, Robert Dallmann, and Yudan Whulanza. The paper describes cheap solutions to several chamber fabrication techniques including photolithography, micromilling, 3D printing, xurography (knife cutting) and screen-printing. The […]

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Make a polarimeter for $350

A polarimeter is used to characterize a sample by measuring the rotation of polarized light when it interacts with the sample. They can cost upwards of ~$10,000, but a $350 DIY high-resolution polarimeter has recently been detailed in a paper by Andrew Harvie , Tom Phillips, and John deMello. The bill of materials for the […]

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