Automated Western Blotting

Western Blots are a ubiquitous technique in biological and biochemical laboratories used to detect a specific protein in a sample using antibody binding. Running a western blot is one of the more mundane and time consuming tasks of a lab researcher. A new paper “Open source automated western blot processor” from Jorge Bravo-Martinez describes a DIY device to automate the process for just $135.50.

The paper details the design, composed of some commercially available as well as 3D printed components. It includes a bill of materials with links for purchasing as well as detailed photos, videos and diagrams for assembly, electronics and even operation. Files are also hosted on a project page by Mendeley. Additionally, the authors show detailed data comparing the clarity of the stains to manual and commercially available western blotting devices. This is how every open source hardware paper should be written.