One of the largest obstacles to two-photon DIY microscopy is the acquisition of a pulsed laser system, which generally hits the $100,000 range. Evan Perillo, Justin McCracken, Daniel Fernée, John Goldak, Flor Medina, David Miller, Hsin-Chih Yeh, and Andrew Dunn have a 2016 paper detailing the construction and characterization of a Ytterbium laser at 1060 […]
Category: DIY
DIY Fluorescence Smartphone Microscopy
We’ve covered several portable microscopy setups before, including Foldscope, wooden scope, and our favorite these little UV magnifiers. We like the latter so much because it is capable of both white light, and UV light, and we found we were capable of doing a little bit of fluorescence microscopy on it. That’s where a 2017 […]
Computers on The Cheap
It’s a Technical Tuesday! Today we are going down the rapids of computer purchasing. This is a primer on purchasing computers on the cheap. We start with prebuilt computers (1), then cover acquiring peripherals (2,3), and finally talk about building your own computers (4,5). This is a living document about a volatile topic, so write […]
3D -Fuge: A New Hand Powered Centrifuge
Last year at around this time we covered Paperfuge, a card stock based centrifuge that could spin QBC capillary tubes samples at ~10,000 g. Using the principles laid out with Paperfuge, Gaurav Byagathvalli, Aaron Pomerantz, Soham Sinha, Janet Standeven, and M. Saad Bhamla have come up with 3D-Fuge detailed in a paper on the bioarxiv […]
OMIS: An Open Millifluidic Inquiry System
OMIS is a 3D tool for performing small-scale chemical synthesis and analysis. The system is Arduino-based and consists of an automated syringe pump run by a cheap stepper motor and reaction vessels. The design is meant to allow for fabrication” in one day”, and can pump fluids at rates between 60 and 300 μL/min. The paper, […]