MesoSPIM: An open-source light-sheet microscope for imaging in cleared tissue

The mesoSPIM (mesoscale selective plane illumination microscopy) project creates open-hardware microscopy platforms for imaging cleared tissue samples. The microscopy setup costs between $170,000 to $240,000 including the optical table and most importantly, the laser itself which will run you between $40,000 to $110,000. This stretches the definition of “On The Cheap”, but the project is […]

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