AttoBright: A single-molecule confocal system built from a 3D-printed scaffold

The AttoBright is a 10×20 cm single-molecule confocal system capable of single photon counting and fluorescence correlation spectroscopy. The scaffolding is designed to minimize the amount of optical components needed, and make those optical components easy to install with automated alignment. A paper by James Brown, Arnaud Bauer, Mark Polinkovsky, Akshay Bhumkar, DominicHunter, Katharina Gaus, […]

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Fluorescent Dyes

A new spin-off of Click Chemistry Tools called Fluoroprobes, is creating generic versions of fluorescent dyes. Our lab recently switched from buying Alexa Fluor® 647 NHS Ester from Thermo Fisher ($339/1mg) to the generic AF 647 NHS Ester from Fluroprobes ($139/1mg). Saves us quite a bit of $$$. We use this dye to label proteins […]

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