Fluorescent Dyes

A new spin-off of Click Chemistry Tools called Fluoroprobes, is creating generic versions of fluorescent dyes. Our lab recently switched from buying Alexa Fluor® 647 NHS Ester from Thermo Fisher ($339/1mg) to the generic AF 647 NHS Ester from Fluroprobes ($139/1mg). Saves us quite a bit of $$$. We use this dye to label proteins […]

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Backyard Radio Astronomy

Want to build yourself a radio telescope? The Society of Amateur Radio Astronomers has a rich catalog of tutorials to build them on the cheap. Of particular interest are instructions to create an “Itty Bitty Radio Telescope” out of a TV Satellite dish, as well as VLF radio reciever kits for $120. And since we […]

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An open-source combiner for inexpensive laser diodes

Scientific-grade lasers are incredibly costly components of modern microscopes. Inexpensive laser diodes are much cheaper, often less than $100, but they have high divergence and an asymmetrical intensity profile, which makes them difficult to efficiently couple into single-mode optical fibers. Instead, they are coupled into multimode fibers, which results in the appearance of laser speckles […]

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